Single Gene Diss, Chromosome Abnormalities, Multifactorial Diss

deoxyribonucleic acid Ab commonities that Manifest as DissYour name HereSTATEMENT OF THE PROBLEMThe purpose is to effect the fol slumping questionsUsing our association of the elementtic code , transcription and adaptation explicate how a bingle component dis may hook from a sportsman . Cite an example of a superstar component dis , explaining what gene has been transmuteed , how this restores the product of this gene , and how this may affect the wellness of the individual carrying the mutation . If possible enunciate what the specific mutation isUsing your knowledge of replication , meiosis , and binding , explain how a chromosome constipation may nobble in the offspring of deuce healthy individuals . Cite an example of a chromosome abnormality , explaining what chromosome or chromosomal segment is missing or duplicated , and how this may affect the health of the individual carrying the abnormalityNot all wound argon sonant to explain , but some (such as breast crab louse colon cancer , type 2 diabetes ) tend to go past more often within acc chromaticited families . Using your knowledge of biotechnology , explain how specific DNA abnormalities can be used to determine a mortal`s chances of growing some diseases , and how this knowledge may continue the development of the diseaseANSWERSSingle gene dis may rise up from a mutationSingle gene dis may arise from mutation . The process of transcription and rendition can be disrupted by these forms of mutations . These mutations include virtuoso base reversal that suppress termination of protein translation , alter patterns of mRNA lap joint during transcription (Garden 2002 . Another mutation is bingle base cut that definitely changes the outcome of mRNA transcription or the protein price chromaticuction of translation . One ex ample of a single booth dis is the sickle ! cell disease . In people with sickle cell disease at least(prenominal) one of the beta hemoglobin subunits in hemoglobin is replaced with hemoglobin S (Genetic Home wing , 2007 . Sickle red course cells become distorted forming a cell that looks like a sickle .

This distorted red blood cell is uneffective to ripey transfer oxygen and may sometimes encumber up in the blood vessels . The low oxygen might and short life span of sickled red blood cells captures genus Anemia to the person afflicted with these heritable dis . This is a form of single base substitution where a normal amino acid (valine ) is repla ced by another one (glutamineChromosome abnormality may arise in the offspring of two healthy individualsThree mechanisms contribute to genetic variation during meiosis and fertilisation . These are independent miscellany of chromosomes , crossing over and random fertilization . Within these triple processes is window for chromosome dis to occur . Meiotic nondisjunction , the ill fortune of the chromosomes to disjoin and posit to to opposite poles , in either the maiden or second meiotic division is the major cause of chromosomal abnormalities (Tissot Kaufman , 2007 . This includes trisomy , which is the mien of 3 chromosomes instead of 2 . rase syndrome , or trisomy 21 , is the classic example of a charitable disease caused by autosomal nondisjunction where some , but not all , touched individuals do survive (Tissot Kaufman , 2007 . Trisomy 21...If you want to get a full essay, order it on our website: OrderCustomPaper.com
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